AP European History
Charles V's rule refers to the reign of Charles V as Holy Roman Emperor and King of Spain from 1519 to 1556, during which he presided over a vast empire that included territories in Europe, the Americas, and parts of Asia. His rule is significant in the context of the New Monarchies as it exemplifies the challenges and complexities faced by monarchs trying to consolidate power, manage diverse regions, and respond to rising religious tensions.