The onset of clinical depression refers to the beginning or initial appearance of symptoms associated with a depressive disorder. It marks the transition from normal mood fluctuations to persistent feelings of sadness, hopelessness, and other characteristic symptoms.
Related terms
Major Depressive Disorder (MDD): Major Depressive Disorder is a specific diagnosis characterized by persistent depressed mood and loss of interest or pleasure in daily activities.
Diathesis-Stress Model: The diathesis-stress model proposes that mental disorders like depression develop due to both genetic predisposition (diathesis) and exposure to significant environmental stressors.
Neurotransmitters: Neurotransmitters are chemical messengers in the brain that transmit signals between nerve cells. Imbalances in certain neurotransmitters have been associated with depression.