Lewis and Clark Expedition: An expedition led by Meriwether Lewis and William Clark, commissioned by President Jefferson to explore and map the newly acquired Louisiana Territory.
Embargo Act of 1807: A law enacted by President Jefferson that prohibited American ships from trading with foreign nations, in an attempt to protect American interests.
Marbury v. Madison: A landmark Supreme Court case during Jefferson's presidency that established the principle of judicial review, giving courts the power to declare laws unconstitutional.