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Affinity refers to the strength of the interaction between an antibody and its specific antigen. It is a measure of how tightly an antibody binds to its antigenic target.
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Epitope: The specific part of an antigen that is recognized and bound by an antibody.
Somatic Hypermutation: A process that occurs in B cells resulting in mutations that increase antibody affinity.
Monoclonal Antibody: An antibody produced from a single clone of cells, specific for one epitope.