Interactions

Definition

Interactions in antimicrobial chemotherapy refer to the effects that drugs have on each other and on microbial cells when combined. These interactions can enhance or diminish the efficacy of treatment.

5 Must Know Facts For Your Next Test

1. Synergistic interactions occur when two antimicrobial drugs work together to produce a greater effect than either drug alone.
2. Antagonistic interactions happen when one drug interferes with the action of another, reducing its effectiveness.
3. Additive interactions result in an effect equal to the sum of the effects of each drug taken separately.
4. Drug-drug interactions can lead to increased toxicity or adverse side effects, impacting patient safety.
5. Monitoring drug interactions is crucial for effective treatment plans and minimizing resistance development.

Review Questions

• What is a synergistic interaction between antimicrobial drugs?
• How can antagonistic interactions impact the effectiveness of antimicrobial therapy?
• Why is it important to monitor drug-drug interactions during antimicrobial chemotherapy?

Related terms

Synergism: An interaction where combined drugs produce a greater effect than the sum of their separate effects.

Antagonism: An interaction where one drug reduces or counteracts the effect of another.

Additive Effect: An interaction where combined drugs produce an effect equal to the sum of their individual effects.