Ammonia toxicity

Definition

Ammonia toxicity occurs when excess ammonia builds up in the bloodstream, which can negatively affect various organs including the lungs. It is often a result of liver dysfunction or metabolic disorders, and can impair respiratory function.

5 Must Know Facts For Your Next Test

1. Ammonia toxicity can exacerbate pulmonary conditions by increasing respiratory alkalosis.
2. Symptoms of ammonia toxicity include confusion, lethargy, and difficulty breathing.
3. Liver dysfunction is a primary cause of ammonia buildup leading to toxicity.
4. Nutrition plays a critical role in managing ammonia levels, with protein intake being particularly important.
5. Patients with compromised lung function are at higher risk for complications from ammonia toxicity.

Review Questions

• What is the relationship between liver dysfunction and ammonia toxicity?
• How does ammonia toxicity impact pulmonary health?
• Why is protein intake crucial in managing ammonia levels in patients?

Related terms

Hepatic Encephalopathy: A decline in brain function due to severe liver disease causing toxins like ammonia to build up in the bloodstream.

Respiratory Alkalosis: A condition where increased respiration reduces carbon dioxide levels, leading to elevated blood pH.

Urea Cycle Disorder: A genetic condition affecting the body's ability to remove waste nitrogen through urea production, potentially leading to high blood ammonia levels.