17-beta-estradiol

Definition

17-beta-estradiol is a potent form of estrogen used in feminizing hormonal therapy to develop female secondary sexual characteristics. It is administered through various routes including oral, transdermal, and injectable forms.

5 Must Know Facts For Your Next Test

1. 17-beta-estradiol helps in breast development and redistribution of body fat to a more feminine pattern.
2. It also plays a role in reducing male-pattern hair growth and softening skin texture.
3. Monitoring blood levels of estradiol is crucial to avoid adverse effects such as thromboembolism.
4. Estradiol can be used alone or in combination with anti-androgens for maximal feminization effects.
5. Patients undergoing 17-beta-estradiol therapy must have regular follow-up appointments for hormone level monitoring and general health assessments.

Review Questions

• What are the primary physical changes induced by 17-beta-estradiol in feminizing hormonal therapy?
• Why is monitoring blood levels of 17-beta-estradiol important during therapy?
• How can 17-beta-estradiol be administered for feminizing hormonal therapy?

Related terms

Anti-androgens: Medications that block the effects of male sex hormones, often used alongside estradiol in feminizing hormone therapy.

Progesterone: Another female hormone that may be added to feminizing hormone regimens to aid breast development.

Thromboembolism: A potential adverse effect of estradiol therapy characterized by the formation of blood clots that can obstruct blood vessels.