Accolate

Definition

Accolate (zafirlukast) is an oral leukotriene receptor antagonist used to manage chronic asthma. It works by blocking the action of leukotrienes, substances in the body that cause inflammation and constriction of airways.

5 Must Know Facts For Your Next Test

1. Accolate is used for long-term management of asthma, not for acute asthma attacks.
2. It is typically taken twice daily, preferably on an empty stomach.
3. Common side effects include headache, infection, and nausea.
4. Liver function tests should be monitored periodically during treatment with Accolate.
5. It may interact with other medications such as warfarin and erythromycin.

Review Questions

• What is the primary use of Accolate in respiratory therapy?
• How often should a patient typically take Accolate?
• Why are liver function tests important when taking Accolate?

Related terms

Leukotriene Modifiers: A class of drugs that includes leukotriene receptor antagonists like zafirlukast and leukotriene synthesis inhibitors.

Xanthines: A class of drugs used to treat asthma and COPD by relaxing bronchial muscles; examples include theophylline.

Mast Cell Stabilizers: Drugs that prevent mast cells from releasing inflammatory substances; commonly used for allergic conditions like asthma.