study guides for every class that actually explain what's on your next test Ghrelin
from class: Pharmacology for Nurses Definition Ghrelin is a hormone produced primarily in the stomach that stimulates appetite and promotes fat storage. It is often referred to as the 'hunger hormone' due to its role in regulating food intake.
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Predict what's on your test 5 Must Know Facts For Your Next Test Ghrelin levels increase before meals and decrease after eating. It activates growth hormone secretagogue receptor (GHS-R) which influences appetite. High ghrelin levels are associated with increased hunger and weight gain. Ghrelin has a role in energy balance by promoting fat storage and decreasing energy expenditure. Pharmacological interventions targeting ghrelin are being researched for weight management therapies. Review Questions What is the primary function of ghrelin? How do ghrelin levels fluctuate in relation to meals? What receptor does ghrelin activate, and what is its significance?
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