disrupts movement due to dopamine loss in the brain. Anti-Parkinsonian medications aim to restore dopamine function or balance , alleviating motor symptoms like tremors and .
Various drug classes target different aspects of the disease. drugs replenish dopamine, while anticholinergics restore neurotransmitter balance. Understanding these medications is crucial for effective symptom management and improved quality of life.
Overview of Anti-Parkinsonian Medications
Introduction to Parkinson's Disease
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Frontiers | On Cell Loss and Selective Vulnerability of Neuronal Populations in Parkinson's Disease View original
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Frontiers | The End Is the Beginning: Parkinson’s Disease in the Light of Brain Imaging View original
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Parkinson's disease, first described by in 1817, is a progressive neurodegenerative disorder affecting movement, balance, and coordination. It primarily results from the loss of dopamine-producing neurons in the , disrupting the and leading to motor symptoms.
Classes of anti-Parkinsonian medications
Dopaminergic drugs enhance dopamine activity in the brain to alleviate Parkinson's symptoms
crosses the blood-brain barrier and converts to dopamine in the brain, replenishing depleted levels
Often combined with to reduce peripheral side effects and increase central nervous system availability