Targeted drug delivery revolutionizes medicine by delivering drugs to specific sites, minimizing side effects and enhancing efficacy. It uses strategies like and to overcome biological barriers and treat localized diseases.
Nanotechnology plays a crucial role in targeted delivery, offering versatile platforms like and . While challenges exist, the future of personalized medicine looks promising, integrating omics data and companion diagnostics for tailored treatments.
Targeted Drug Delivery Concepts
Importance of targeted drug delivery
Top images from around the web for Importance of targeted drug delivery
Frontiers | Targeted Drug Delivery Systems for Kidney Diseases View original
Is this image relevant?
Frontiers | Current Trends of Targeted Drug Delivery for Oral Cancer Therapy View original
Is this image relevant?
Frontiers | Platelet Membranes Coated Gold Nanocages for Tumor Targeted Drug Delivery and ... View original
Is this image relevant?
Frontiers | Targeted Drug Delivery Systems for Kidney Diseases View original
Is this image relevant?
Frontiers | Current Trends of Targeted Drug Delivery for Oral Cancer Therapy View original
Is this image relevant?
1 of 3
Top images from around the web for Importance of targeted drug delivery
Frontiers | Targeted Drug Delivery Systems for Kidney Diseases View original
Is this image relevant?
Frontiers | Current Trends of Targeted Drug Delivery for Oral Cancer Therapy View original
Is this image relevant?
Frontiers | Platelet Membranes Coated Gold Nanocages for Tumor Targeted Drug Delivery and ... View original
Is this image relevant?
Frontiers | Targeted Drug Delivery Systems for Kidney Diseases View original
Is this image relevant?
Frontiers | Current Trends of Targeted Drug Delivery for Oral Cancer Therapy View original
Is this image relevant?
1 of 3
Targeted drug delivery selectively delivers drugs to specific sites in the body (tumors, organs, cells)
Facilitates the treatment of localized diseases or conditions (brain tumors, neurological disorders)
Strategies for targeted delivery
Ligand-mediated targeting
Utilizes ligands that specifically bind to receptors or antigens on target cells (antibodies, peptides, aptamers)
Enables and cellular uptake of drug-loaded carriers
Examples include antibody-drug conjugates (ADCs) (trastuzumab emtansine for HER2-positive breast cancer) and folate receptor targeting (folate-conjugated nanoparticles for ovarian cancer)
Stimuli-responsive systems
Respond to specific internal or external stimuli to trigger drug release