15.2 Antiviral drug resistance and combination therapies
3 min read•august 1, 2024
is a major hurdle in fighting viral infections. It occurs when viruses mutate, allowing them to replicate despite medication. This leads to , increased healthcare costs, and the spread of resistant strains.
are a powerful tool against resistance. By targeting multiple viral processes, they create a higher barrier to . This approach enhances effectiveness, reduces viral rebound, and improves long-term suppression of infections like and .
Antiviral drug resistance
Definition and implications
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Top images from around the web for Definition and implications
Frontiers | Strategies to overcome HIV drug resistance-current and future perspectives View original
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Vaccines and Anti-Viral Drugs for Treatment | Biology for Majors II View original
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Frontiers | The Signaling Pathways, and Therapeutic Targets of Antiviral Agents: Focusing on the ... View original
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Frontiers | Strategies to overcome HIV drug resistance-current and future perspectives View original
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Vaccines and Anti-Viral Drugs for Treatment | Biology for Majors II View original
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Antiviral drug resistance develops when viruses replicate despite the presence of inhibitory medications
Genetic mutations in viral genomes alter drug targets or virus entry mechanisms into host cells
Drug-resistant viruses continue replicating and progressing disease during antiviral therapy
Resistant strains limit treatment options for patients and create public health challenges through transmission
Healthcare costs increase due to more expensive or extended treatments for resistant infections
Genetic testing monitors drug resistance to guide treatment decisions and develop new antiviral strategies